The CDC estimates that 19 drug-resistant pathogens cause 9.7 million infections and more than 50,000 deaths annually in the U.S., with resistance continuing to outpace development of new treatments. "The agency considers this problem to be one of our most urgent public health threats," reports NBC News. From the report: The report is the CDC's first comprehensive assessment of these drug-resistant pathogens in seven years. [...] The new report offers a detailed picture of these threats in the U.S., including a ranking of which are the most urgent concerns, based on the number and severity of infections they cause and how easily preventable or transmissible they are. The ranking also factors in how many treatment options exist and their costs. [...] The report estimates that 19 drug-resistant germs cause 9.7 million infections annually in the U.S. Of these, four pathogens are ranked as most worrisome, including the fungus Candida auris and the bacteria that causes gonorrhea, which has become resistant to all but one class of antibiotics used to treat it. The other two urgent threats, according to the CDC, are the bacteria Acinetobacter and Enterobacterales, both of which are resistant to a class of antibiotics widely considered a "last resort" for patients. In addition, the report adds a new bacteria to the list of "concerning" threats, which are considered less worrisome but still warrant monitoring: neisseria meningitidis, which causes meningococcal disease. The rare but life-threatening illness can be prevented through childhood vaccinations, but the bacteria that causes it is slowly developing a resistance to penicillin and another antibiotic called ciprofloxacin. The report also offers some good news: The CDC determined that the bacteria Clostridioides difficile, or "C. diff," which causes diarrhea and inflammation of the colon and can be deadly, is causing fewer cases year over year. The agency downgraded it to a serious threat, whereas it was categorized as urgent in the prior version of the report, which came out in 2019.

Read more of this story at Slashdot.

An anonymous reader quotes a report from CBS News: Greenhouse gas concentrations in the atmosphere rose to record highs in 2025, locking in climate impacts that will persist for centuries, the United Nations said on Tuesday. Levels of the three main greenhouse gases -- the climate-warming carbon dioxide, methane and nitrous oxide -- all rose to unprecedented figures in 2025, the U.N.'s weather and climate agency said. The World Meteorological Organization said the rise would lead to more long-term temperature increases for the planet. The bulletin looks at greenhouse gas concentrations -- the amount of those gases in the atmosphere -- rather than new annual emissions amounts as the world burns more coal, oil and gas. In 2025, carbon dioxide concentrations were at 426.8 parts per million (ppm); methane at 1,948 parts per billion, and nitrous oxide at 339.1 parts per billion. That takes them, respectively, to 153%, 267% and 126% of the pre-industrial levels witnessed before 1750. Of the three major greenhouse gases, CO2 accounts for about 66% of the warming effect on the climate. Around half of the total CO2 emitted each year remains in the atmosphere; the rest is absorbed by the land and oceans. From 2024 to 2025, the global average concentration of CO2 rose by 2.8 ppm -- smaller than the record surge from 2023 to 2024 of 3.6 ppm. WMO senior scientific officer Oksana Tarasova said this reflected the "recovery of the land carbon sinks and reduced fire carbon emissions in 2025 after the strong 2023/2024 El Nino," the naturally occurring, climate-warming weather phenomenon. "However, a 2.8 ppm annual increase is still a substantial addition of carbon to the atmosphere from fossil fuel burning." It is also above the average growth rate for the past decade of 2.6 ppm -- a figure that stood at 0.8 ppm in the 1960s. "Another year, another new record," said WMO Deputy Secretary-General Ko Barrett. "Greenhouse gases are trapping an unprecedented amount of heat in the atmosphere, providing energy for more extreme weather and associated risks to our economies and societies. Further reading: UN Says Breaching 1.5C Warming Limit Is 'Imminent and Unavoidable'

Read more of this story at Slashdot.

Have you seen this?

If you haven't, you should. I think everyone needs to. Wealth inequality on a scale this extreme is almost impossible to explain. You have to experience it to understand.

Go ahead. Try it out.

Where is the top of this graph? Good question. Keep scrolling up. Last time I did this it took me 12 minutes and 51 seconds, but the whole time I had a way out.

We get a button on the screen that lets us punch out any time we want: I quit. But do other Americans get an easy way out of the most extreme wealth concentration in history, piled up together all the way down there at the bottom of this graph?

No. They don't.

That's why we built this website. That's why I supported the updated 2026 wealth inequality video series, because 14 years ago, the original video changed how I thought about the world. I watched it again and again, year after year, because it shows something we feel, but rarely see so clearly — the obscene concentration of wealth and power in this country.

People deserve to see the facts plainly, visually, with sources and methodology attached. Politizane, The Onion and Garbage Day retained full control over their work. I did not tell anyone what to make, what to say, or how to say it. I told everyone involved the same thing I'm telling you right now – this is not for me, or any organization. It is for the public. It is for We, The People.

I used to be very dismissive of so-called "walking simulators", games where no real choice is offered, it's just an experience. But this graph isn't a game – these are people's actual lives. No one is forcing you to visit this website, no one is making you scroll up endlessly. The experience, then, is about endurance in the face of the relentless task of simply living your daily life with almost nothing, surviving as long as you can without reaching for the "I Quit" button. That's the experience the vast majority of Americans are having. It is harrowing.

As we built the website (Geoff Dalgas, my friend who helped me build Stack Overflow, did all the technical work) and tested it, as I obsessively scrolled upwards so many times, I slowly realized the whole thing is supposed to be inconvenient. The further you climb on this vast scale, the longer this seemingly endless scrolling goes on, the more the reality sinks in... how obscene all of it is. In order to understand the suffering of others, you must be willing to endure and suffer a little bit yourself. In this case, suffering is a feature.

Early iterations of the website had automatic scrolling, or rapid jumps, but I felt that wasn't right and should not be allowed. You need to do the work, make a physical action to scroll the entire way. We even stop you from scrolling at certain milestones.

This is a forced stop because no one should blindly scroll past 36 million Americans living in poverty, while at the same time we could eliminate all poverty in this country for $177 billion.

But we, for some reason, choose not to. We choose to let people suffer in desperate poverty. That's also suffering as a feature. In an era of unprecedented wealth, why shouldn't that money be out there doing something, somewhere, for someone?

I've spent my whole career talking about software usability, and I never thought I would design software that chooses to actively punish the user, but the data itself is the pain. Representing the massive numbers of wealth inequality with a linear scale is the only honest way to present this data. Do you have any idea how many pages it would take to print this graph in its entirety, representing both the richest American at the top, and the poorest American at the bottom?

What you should print out is this is 8 page foldable version of the graph, designed to be a relatable 6 feet, 6 inches, the average NBA player height. Show everyone what the most obscene centerfold of all time looks like. Let them see.

I challenge everyone to climb the graph on dreamagainusa.org as far as you want to.

If you do reach the so-called "top", I have a question.

Was it worth it?

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Snake is a good weekend project. The rules fit on a napkin, and a playable version still needs a game loop, keyboard input, collision checks and some saved state. It also happens to be a nice way to see how far a plain Aurelia 2 component gets you.

By the end of this post you’ll have a full game in one component: a 20 by 20 board, a snake that grows when it eats, arrow key and WASD controls, an on-screen pad for phones, and a high score kept in localStorage. There are three files, under 300 lines in total, and no dependencies beyond Aurelia.